What is it about?

This article is a comprehensive review of EGFR-TKIs as first-line treatment for patients with advanced NSCLC. In addition to comparing osimertinib (standard of care) with first- and second-generation TKIs, this review also compares first- and second-generation TKIs with each other. Further, this review discusses the cost-effectiveness of osimertinib in comparison with first-and second-generation TKIs.

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Why is it important?

This study reviewed articles that assessed tyrosine kinase inhibitors (TKIs) for advanced NSCLC and developed an appropriate treatment plan for patients in low-income countries.

Perspectives

This article helps oncologists with limited resources to decide on treatment for EGFR-positive NSCLC and also helps researchers by reviewing and discussing RCTs.

Mousa Alali
Damascus University

Read the Original

This page is a summary of: Optimizing the Treatment for Advanced Non–Small-Cell Lung Cancer with Mutated Epidermal Growth Factor Receptor in Low-Income Countries: A Review, Journal of Immunotherapy and Precision Oncology, June 2023, Innovative Healthcare Institute,
DOI: 10.36401/jipo-22-29.
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