Cone-Beam CT Imaging for Transbronchial Biopsies in Children

What is it about?

This study is the first to explore the use of cone-beam computed tomography (CBCT) guided transbronchial biopsy (TBBx) in children. Our results show that this technique is safe and effective. By using augmented fluoroscopy, we improved the accuracy and precision of the procedure. Although our study had a high diagnostic success rate, it could be even better if we performed an additional CBCT scan with the biopsy tool inside the nodule to verify its position. However, this extra step was not done routinely to reduce radiation exposure. Other methods for lung biopsy in children, like endobronchial ultrasound and virtual CT navigational bronchoscopy, have shown similar success rates and safety. Some newer techniques, like electromagnetic and robotic bronchoscopy, are promising but have been tested on fewer patients. More invasive methods, such as thoracoscopic or open lung biopsies, have high success rates but also come with greater risks and require hospital stays. While our study shows positive results, it has limitations, such as a small sample size and lack of direct comparison with other techniques. Our study was also conducted in a specialized center, which might affect how widely the findings can be applied. More research with larger groups and direct comparisons is needed to confirm the benefits of CBCT-guided TBBx in children.

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