What is it about?
A comparative study between a normal and an inflamed appendix wall of 50 patients admitted to Al-Ramady teaching hospital (age range between 15 to 42) years old was done by culturing on specific media, using the API system(analytical profile index) for specific diagnosis then colony counting by standard plate count.
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Why is it important?
The results showed significant differences between the flora of histologically normal and acutely inflamed appendices in the number of the same bacteria. Bacteroides species, Escherichia coli, and streptococcal species were the commonest organisms isolated and were found in counts of 103 to 108 organisms per gram of tissue. Bacteroides species were most commonly the dominant flora in both normal and inflamed appendices.
Perspectives
The decrease in the equal amount of bacterial colonies in acute inflammation of the appendix compared to normal appendix makes primary bacterial infection an unlikely etiological factor in the pathogenesis of appendicitis. Still, it is the result of the growth of the already existing bacteria and since some of these bacteria showed a statistically significant with appendicitis, they could be used as a marker for the diagnosis by adding it to the Alvarado Score for Acute Appendicitis.
Assistant Professor Yasir Mufeed Abdulateef
University of Anbar
Read the Original
This page is a summary of: A BACTERIOLOGICAL COMPARISON BETWEEN A NORMAL AND AN INFLAMED APPENDIX, January 2020, Africa Health Research Organization,
DOI: 10.36295/asro.2020.231033.
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