What is it about?

The purpose of this review is to provide an overview of the advances in ingestible capsule systems and their use for monitoring the gastrointestinal tract. We address topics such as the structure and functions of the gastrointestinal tract, FDA guidelines, hardware and software technologies, microrobotics, closed-loop feedback, physiological sensing, nerve stimulation, sampling and delivery, panoramic imaging with adaptive frame rates, rapid reading software, biocompatible materials and batteries, edible electronics, and alternative energy sources. Clinical studies are discussed to examine their safety and effectiveness, and the current challenges and outlook are summarized.

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Why is it important?

By reviewing hardware and software technologies used for capsule endoscopy and remote patient monitoring, this paper examines the up-to-date progress in ingestible capsule systems that offer a safe and comfortable means of tracking the gastrointestinal tract. It goes on to discuss the FDA guidelines for ingestible wireless telemetric medical devices, as well as the advanced features incorporated in the capsule systems such as microrobotics, closed-loop feedback, physiological sensing, nerve stimulation, sampling and delivery, adaptive frame rates, and software. It looks into the examples of both experimental and commercialized capsule systems, along with their sensors, devices, and circuits for gastrointestinal health monitoring. Additionally, the paper presents research about biocompatible materials, batteries, edible electronics, and alternative energy sources for ingestible capsule systems. Lastly, it reviews the clinical studies and assesses the performance indicators related to the safety and effectiveness of ingestible capsule procedures. It also outlines the challenges and the future outlook for the risks to health, clinical testing and approval process, and technology adoption.

Perspectives

In this review, we focus on the hardware and software technologies used for the purpose of gastrointestinal tract monitoring in a safe and comfortable manner. We review the FDA guidelines for ingestible wireless telemetric medical devices, and the features incorporated in capsule systems such as microrobotics, closed-loop feedback, physiological sensing, nerve stimulation, sampling and delivery, panoramic imaging and rapid reading software. Both experimental and commercialized capsule systems with their sensors, devices, and circuits are discussed. Furthermore, the advances in biocompatible materials and batteries, edible electronics and alternative energy sources for ingestible capsule systems are presented. The clinical studies are reviewed to examine the safety and effectiveness of capsule procedures and the current challenges and outlook are summarized.

Prof Santosh Pandey
Iowa State University

Read the Original

This page is a summary of: Video Capsule Endoscopy and Ingestible Electronics: Emerging Trends in Sensors, Circuits, Materials, Telemetry, Optics, and Rapid Reading Software, Advanced Devices & Instrumentation, November 2021, American Association for the Advancement of Science,
DOI: 10.34133/2021/9854040.
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