What is it about?

The immune system is capable of recording immunological events and this record is used to handle future stimuli of the system. In analogy to records of the brain this is called memory. Immunological memory is built up by the generation of specialized cells, which carry the molecular imprint of past events. There are classes of such cells, each contributing in slightly different ways to immune function.

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Why is it important?

Vaccination is the arteficial, designed generation of immunological memory, therefore our understanding ofmemory formation helps the better design of vaccines.

Perspectives

Going beyond the cell-biological characteriation of memory cells, the interplay between these cells reveals the architecture of the immune system, which is basically the network of memory cells and effector molecules.

József Prechl
Diagnosticum

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This page is a summary of: Multiple Levels of Immunological Memory and Their Association with Vaccination, Vaccines, February 2021, MDPI AG,
DOI: 10.3390/vaccines9020174.
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