What is it about?
The hydroethanolic bark extract has a high polyphenol content, and the loliolide was discovered for the first time in this species. No toxic effects of the extract were found in in vitro cytotoxicity tests, mutagenicity tests, and no oral toxicity. These findings suggest that EBHE has potential as a source of bioactive molecules, and it can be used safely in traditional medicine and in the development of herbal medicines for application in the public health system.
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Why is it important?
Additionally, there were no adverse effects of oxidative stress, cholesterol, triglycerides, glycemia, or liver and kidney function biochemical markers. Mild hypoglycemic and hypolipidemic effects were evidenced with repeated oral doses. Regarding the antioxidant parameters, data indicated a potential protective effect since the glutathione content showed no significant change, and SOD and GPx exhibited a significant increase
Perspectives
These findings confirm P. parvifolium’s safe usage in conventional medicine and point to a possible alternative therapeutic use in the public health system. P. parvifolium may also be a viable source of bioactive chemicals.
Dr. Jorge A. López
Read the Original
This page is a summary of: Pseudobombax parvifolium Hydroalcoholic Bark Extract: Chemical Characterisation and Cytotoxic, Mutagenic, and Preclinical Aspects Associated with a Protective Effect on Oxidative Stress, Metabolites, June 2023, MDPI AG,
DOI: 10.3390/metabo13060748.
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