What is it about?
This editorial aims to investigate whether methyl donor nutrient supplementation could have a beneficial effect on metabolic syndrome and its components in humans.
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Why is it important?
Gene susceptibility to MetS in humans interacts with diet, which can induce changes in gene expression. These changes may be a target for inducing novel therapeutic strategies for modulating the progression to MetS using dietary manipulation such as supplementation with methyl-donor nutrients.
Perspectives
Gaining a better understanding of epigenetic regulation of gene expression in MetS would be useful to guide future RCTs for nutritional interventions based on methyl-donor supplements that may alter the epigenetic marks of genes, thereby modulating the progression of MetS.
Dr Naser Alsharairi
Griffith University
Read the Original
This page is a summary of: Is There an Effect of Methyl Donor Nutrient Supplementation on Metabolic Syndrome in Humans?, Medical Sciences, January 2020, MDPI AG,
DOI: 10.3390/medsci8010002.
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