What is it about?

having a microscope so powerful it can see living cells in action, right inside your eye! That's what scientists are doing with some cool new technology called Two-photon excitation microscopy (TPM) and multiphoton fluorescence microscopy (MPM). Here's the scoop: What makes these microscopes special? They can see tiny things moving inside living tissue They work great on eyes because eyes are clear and easy to access What are scientists using these microscopes for? Studying eye immune cells: They found that some cells they thought were one type might actually be another They're looking at special cells that help protect eyes from viruses Watching how the eye repairs itself: They can see how stem cells in the eye help make new cells to keep the eye surface healthy Looking at eye injuries and healing: They can see how the white part of the eye (sclera) and the clear covering (conjunctiva) heal after surgery This is especially useful for understanding how eyes heal after glaucoma surgery Testing new medicines: They can watch how drugs move through different parts of the eye

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Why is it important?

These super-powered microscopes are helping scientists understand eyes better than ever before. This could lead to new treatments for eye diseases and better ways to keep our eyes healthy.

Perspectives

This technology is changing how we study eyes and could make a big difference in eye care in the future.

Prof Louis Tong
National University of Singapore

Read the Original

This page is a summary of: Two-Photon and Multiphoton Microscopy in Anterior Segment Diseases of the Eye, International Journal of Molecular Sciences, January 2024, MDPI AG,
DOI: 10.3390/ijms25031670.
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