What is it about?

This review looks at how different things in our environment, both outside and inside our bodies, can affect diseases of the eye's surface. Scientists are particularly interested in how tiny organisms living on our eyes (the eye microbiome) might play a role in these conditions.

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Why is it important?

Understanding what causes eye surface diseases is important because: These conditions can be really uncomfortable and even lead to vision loss Knowing what triggers these problems could help prevent or treat them better The tiny organisms on our eyes might be more important than we thought

Perspectives

Here's what researchers are finding: Eye surface diseases can be caused by things outside our body (like pollution or stress) and things inside our body (like the microbes on our eyes or in our gut) New technology is helping scientists study the tiny organisms living on our eyes In people with eye surface diseases, these organisms are often different from those in healthy eyes We're not sure if these changes in eye microbes cause the diseases or if they happen because of the diseases Understanding all these factors (called "exposomes") could help us figure out why some people get eye inflammation and scarring This knowledge might lead to new ways to prevent or treat eye surface diseases This research is like putting together a puzzle to understand why some people get eye problems. It's showing us that there's more to eye health than just what we can see – tiny organisms and our environment play big roles too. By looking at the whole picture, from the air we breathe to the microbes on our eyes, scientists hope to find new ways to keep our eyes healthy and treat problems when they occur.

Prof Louis Tong
National University of Singapore

Read the Original

This page is a summary of: Impact of Exposomes on Ocular Surface Diseases, International Journal of Molecular Sciences, July 2023, MDPI AG,
DOI: 10.3390/ijms241411273.
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