Very Low-Calorie Ketogenic Diet, the infant gut microbiota and asthma.

What is it about?

The aim of this review is to identify the potential role of SCFAs that underlie the effects of VLCKD during pregnancy and lactation on the infant gut microbiota, and explore whether it incurs significant implications for reducing asthma.

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Why is it important?

SCFAs are key microbial metabolites that mediate the relationship between VLCKD during pregnancy and lactation, and the infant gut microbiota. The VLCKD regimen, including sources of dietary fiber, fats (high in PUFA, moderate in MUFA and low in SAT) and plant-based protein, may influence SCFA-producing bacteria in gut microbiota, and therefore, lead to an anti-inflammatory state and a decreased risk of asthma.