What is it about?

KCa channels are involved in inflammation. Treatment with a KCa blocker may be a method of treating inflammation in the ocular surface. We synthesize a nanoliposomal formulation of the KCa blocker, so that sustained release do not require frequent instillation of the medication, thus allowing for greater patient compliance.

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Why is it important?

Ocular surface inflammation affects many common diseases such as dry eye, ocular allergies, infections and many other conditions.

Perspectives

Ion channel therapeutics may play a role in treatment of dry eye

Prof Louis Tong
National University of Singapore

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This page is a summary of: Topical Delivery of Senicapoc Nanoliposomal Formulation for Ocular Surface Treatments, International Journal of Molecular Sciences, September 2018, MDPI AG,
DOI: 10.3390/ijms19102977.
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