What is it about?

This paper explores the mechanisms involved in the therapeutic potential of flavone-rich extracts from S. baicalensis in nicotine-induced NSCLC and asthma.

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Why is it important?

The significant link between NSCLC and asthma could have health benefits for smokers in terms of using S. baicalensis and its compounds. Given that S. baicalensis is used in several therapeutic practices, targeting the flavones extracted from such a plant and understanding its molecular mechanisms of action might help in providing new therapeutic strategies for the treatment of NSCLC and asthma, particularly in smoker patients.

Perspectives

Further mechanistic studies to explore the link between asthmatic bronchial fibroblasts and NSCLC development are needed to ascertain the role of flavone compounds as potentially therapeutic in nicotine-induced asthma. Further studies are also needed to investigate the therapeutic efficacy and safety of S. baicalensis and its compounds for the treatment of smoker patients with NSCLC and asthma.

Dr Naser Alsharairi
Griffith University

Read the Original

This page is a summary of: Scutellaria baicalensis and Their Natural Flavone Compounds as Potential Medicinal Drugs for the Treatment of Nicotine-Induced Non-Small-Cell Lung Cancer and Asthma, International Journal of Environmental Research and Public Health, May 2021, MDPI AG,
DOI: 10.3390/ijerph18105243.
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