What is it about?
This paper describes morphological, vascular and molecular biological findings in neovascular AMD model with human VEGF-A165 expression.
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Why is it important?
Created mouse model of subretinal neovascularization is useful for mimicking the pathogenesis of AMD, studying the effects of human VEGF-A165 in the retina, and evaluating anti-VEGF treatments for choroidal neovascularization.
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This page is a summary of: Human Vascular Endothelial Growth Factor A165 Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration, Genes, August 2018, MDPI AG,
DOI: 10.3390/genes9090438.
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