What is it about?
We aimed to investigate the effect of weight status on inflammation-related markers and thyroid function tests in overweight and obese pediatric patients.
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Why is it important?
The objectives of the present study were: (i) to investigate the effect of weight status defined according to WHO criteria on measures of laboratory tests performed in pediatric patients (as routine evaluation according to the national guideline); (ii) to evaluate the effect of weight status on inflammation-related markers in pediatric patients; and (iii) to explore the relationships between the inflammation-related markers and thyroid profile in the overweight or obese pediatric patients
Perspectives
Total absolute white-blood cells count (WBC) proved to be a reliable inflammationrelated marker in pediatric obesity prior to the onset of metabolic syndrome, but this result needs to be validated in the context of all possible covariates. The changes in absolute lymphocyte and polymorphonuclear neutrophils counts with age may influence absolute WBC count’s role in reflecting subclinical inflammation. Laboratory changes suggestive of subclinical and overt hypothyroidism indicate an obesity-driven thyroid dysfunction, possibly inflammation-mediated.
PhD, MD racataianu nicoleta
UMF Iuliu Hatieganu Cluj-Napoca Romania
Read the Original
This page is a summary of: Inflammation-Related Markers and Thyroid Function Measures in Pediatric Patients: Is the Grade of Obesity Relevant?, Diagnostics, March 2021, MDPI AG,
DOI: 10.3390/diagnostics11030485.
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