What is it about?
Killing cancer cells may not be successful as chemotherapy and immune blockers cause damages in both patients and their tumors. Estrogen is a cure of cancer, rather than being a breast cancer initiator. Attack against somatic mutations in tumors inhibits the self directed effort for DNA repair. There is no need of vaccination against tumors as the immune system knows better the means of curing cancer.
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Why is it important?
There is no need of attack on altered genes and immune blockade against tumor as estrogen treatment or activation of estrogen receptors is capable of rectifying genomic stability and promoting apoptotic tumor death. Excessive breast cancer burden in regions positioned near to Arctic pole is attributed to light deficiency associated melatonin excess and suppressed estrogen signaling.
Perspectives
Endogenous estrogen is an excellent therapy against breast cancer as facilitates self directed death of tumor cells and strengthens the immune defense against cancer. Using natural estrogen even is high doses and stimulation of estrogen receptor expression is the adequate therapy of breast cancer.
professor Zsuzsanna Suba
National Institute of Oncology Budapest
Read the Original
This page is a summary of: Estrogen Regulated Genes Compel Apoptosis in Breast Cancer Cells, Whilst Stimulate Antitumor Activity in Peritumoral Immune Cells in a Janus-Faced Manner, August 2024, MDPI AG,
DOI: 10.3390/curroncol31090362.
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