What is it about?
Tested pathogens: 6 Enterobacterales and 3 non-fermenting bacilli. Aztreonam plus avibactam was the most effective combination, able to restore aztreonam susceptibility in four out of nine tested isolates, reaching in some cases a 128-fold reduction of the MIC of aztreonam.
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Why is it important?
It confirms aztreonam + avibactam as an active combination against ESBL and MBL
Read the Original
This page is a summary of: Antimicrobial Activity of Aztreonam in Combination with Old and New β-Lactamase Inhibitors against MBL and ESBL Co-Producing Gram-Negative Clinical Isolates: Possible Options for the Treatment of Complicated Infections, Antibiotics, November 2021, MDPI AG,
DOI: 10.3390/antibiotics10111341.
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