What is it about?
Drink spiking is a serious safety issue because it’s often linked to crimes like theft and sexual assault. Detecting the drugs used in these cases is difficult because they are present in very tiny amounts and drinks are complex mixtures. This review looks at how advanced laboratory techniques—gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS)—can help identify these drugs in spiked drinks. GC-MS is especially powerful because it can detect extremely small amounts of drugs, tell apart chemicals that look similar, and analyse several substances at once. The review explains how these methods work for drugs like GHB and benzodiazepines, and why special steps are needed to make the drugs easier to detect. It also discusses the challenges of testing different types of drinks and the need to keep improving these techniques as new drugs appear. Overall, GC and GC-MS are essential tools for forensic science, helping investigators get accurate results that are crucial for legal cases and public safety.
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Why is it important?
This research is important because: Drink Spiking is a Serious Public Safety Issue It’s linked to crimes like sexual assault and theft, making fast and accurate detection of drugs critical for protecting people and supporting investigations. Health Risks from Hidden Drugs Victims often consume dangerous substances without knowing, which can cause severe health effects or even death. Detecting these drugs quickly can save lives. Detection is Extremely Challenging Drugs used in spiking are present in tiny amounts and drinks are complex mixtures, so advanced techniques like GC and GC-MS are essential for accurate results. GC-MS Provides High Accuracy and Reliability It can identify drugs even at very low levels and distinguish between chemicals that look similar, which is vital for forensic evidence in court. Keeps Pace with Evolving Drug Trends New drugs appear regularly, so improving detection methods ensures law enforcement and forensic labs stay ahead.
Perspectives
Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations.
Dr. Kevin Honeychurch
University of the West of England
Read the Original
This page is a summary of: Applications of Gas Chromatography and Gas Chromatography-Mass Spectrometry for the Determination of Illegal Drugs Used in Drink Spiking, Chemosensors, June 2025, MDPI AG,
DOI: 10.3390/chemosensors13060205.
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