Encapsulated probiotics disturb human core microbiome

What is it about?

Encapsulated probiotics disturb human core microbiome

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Why is it important?

To the best of our knowledge, ignoring the high colonization potential of the bacterial probiotics and administering them in high concentration, despite possessing some favorable probiotic characteristics but lacking the survival traits and persistence capabilities, may disturb the evolutionarily-developed intestinal balance and in time give rise to some serious inadvertent imperceptible side effects. Intestinal microflora should be considered as complex systems. Hence, even trivial alterations in microflora of intestine accumulated in a long-term process may elicit drastic changes within the composition and setting of intestine, which can in return impact the intestinal microbiome biofunctions and metabolomes as well as human normal physiology in a holistic manner.