What is it about?
This review describes the current findings concerning the effects of thyroid hormone receptors on cerebellar development and function. Most of the findings came from advances in the transgenic mouse models. Since 1996, mice with mutated or absent thyroid hormone receptors isoforms have been one of the main tools to study the effect of thyroid hormones in important organs as Central Nervous System.
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Why is it important?
Our review organized a useful table putting together the main transgenic animals in witch the cerebellar function and development was carefully studied.
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This page is a summary of: Thyroid Hormone Role on Cerebellar Development and Maintenance: A Perspective Based on Transgenic Mouse Models, Frontiers in Endocrinology, May 2014, Frontiers,
DOI: 10.3389/fendo.2014.00075.
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