Green Extraction of Milletia Pinnata Oil for Herbal Nano Hydrogel Development

What is it about?

The study aimed to develop a nano hydrogel incorporating bioactive compounds extracted from M. pinnata oil and N. jatamansi root extract using green hydrodistillation technology. Gas Chromatography-Mass Spectrometry (GC-MS) analysis identified various compounds with potential biological activities, including antimicrobials and anti-inflammatory agents. A nano hydrogel was synthesized using low-energy-assisted emulsion polymerization and exhibited stability, homogeneity, and particle size of 196.7 nm. The nano hydrogel displayed antimicrobial activity against both Gram-positive and Gram-negative bacteria and anti-inflammatory properties by inhibiting protein denaturation. These findings highlight the potential of the isolated compounds and the developed nano hydrogel for various applications in medicine and biotechnology. Further research is needed to explore their therapeutic potential and optimize their utilization.

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Why is it important?

This research is important because it contributes to the growing field of natural compound isolation and nanomaterial development. The study successfully isolated bioactive compounds from Milletia pinnata oil and Nardostachys jatamansi root extract, which have potential biological activities, including antimicrobial and anti-inflammatory agents. The nano hydrogel developed using these compounds has promising applications in medicine and biotechnology, including drug delivery systems, wound healing, and tissue engineering. Key Takeaways: 1. The study isolated bioactive compounds from M. pinnata oil and N. jatamansi root extract, which showed potential antimicrobial and anti-inflammatory activities. 2. A nano hydrogel was synthesized using these compounds, exhibiting homogeneity, stability, and particle size of 196.7 nm. 3. The nano hydrogel demonstrated promising antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as anti-inflammatory properties by inhibiting protein denaturation. 4. Further research is needed to explore the therapeutic potential and optimize the utilization of these isolated compounds and developed nano hydrogel.