What is it about?
Human studies of DNA and rRNA sequences are related to Parkinson's disease (PD) and Multiple System Atrophy (MSA). These human findings were compared to results in PD and MSA mouse models. We found that there were similarities between humans and mice and that our drugs improved bacterial pools in some of the aging mice.
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Why is it important?
These findings are important because they may identify markers for PD and MSA diagnosis and show that our novel drugs improve mouse bacterial pools in the gut.
Perspectives
Read the Original
This page is a summary of: A Pilot Microbiota Study in Parkinson’s Disease Patients versus Control Subjects, and Effects of FTY720 and FTY720-Mitoxy Therapies in Parkinsonian and Multiple System Atrophy Mouse Models, Journal of Parkinson’s Disease, January 2020, IOS Press,
DOI: 10.3233/jpd-191693.
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