Intracranial venous sinus thrombosis as unusual presentation of Bing-Neel syndrome: case

What is it about?

Waldenstrom macroglobulinemia, a lymphoplasmacytic lymphoma, accounts for 2% of monoclonal gammopathies. Neurological complications occur in 25% of these patients with peripheral nerve infiltration or serum hyperviscosity syndrome. Direct malignant infiltration of the brain is rare and is referred to as Bing-Neel syndrome.

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Why is it important?

To our knowledge, this is the first report of diffuse neoplastic infiltration of the principal intracranial venous sinuses in Bing-Neel syndrome.