What is it about?

This randomised controlled study looks into the incidence and outcomes such as morbidity and mortality, ICU and hospital stay of patients undergoing bypass surgery from the effect of postoperative atrial fibrillation which is the commonest complication of coronary artery bypass surgery.

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Why is it important?

This study which is prospective in nature confirms the existing facts about the deleterious effects of postoperative atrial fibrillation after bypass surgery although the ultimate aim is to assess the possible mitigating factor - tocotrienol, an isomer of vitamin E - which will only be analysed when the study is unblinded in the end.

Perspectives

This study took three years to be completed despite the COVID-19 pandemic and whether or not the antioxidant tocotrienol helps prevent atrial fibrillation after bypass surgery will only be known after the study is unblinded.

Dato' Dr Ahmad Farouk Musa
Monash University

Read the Original

This page is a summary of: Incidence and Outcomes of Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting of a Randomized Controlled Trial: A Blinded End-of-cycle Analysis, Reviews in Cardiovascular Medicine, April 2022, IMR Press,
DOI: 10.31083/j.rcm2304122.
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