Beta-cell function in people with type 1 diabetes is associated with improved post-exercise glucose

What is it about?

A large variability in the glucose response to exercise exists in individuals with type 1 diabetes. We have shown for the first time that individuals with a high amount of beta-cell function have improved glucose control after exercise compared to individuals with either none or low beta-cell function. This may partially explain some of the variation in glucose response after exercise in individuals with type 1 diabetes.

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Why is it important?

Understanding why individuals glucose responses to exercise differ may lead to more personalised advise on adjusting insulin and carbohydrates around exercise, hopefully leading to improved glucose control and reduced time spent in hypo and hyperglycemia. Beta-cell function (as measured by C-peptide) may be useful in identification of patients most at risk and who need the most support for exercise-associated dysglycemia. Future exercise research should also consider levels of C-peptide as a factor that may impact study outcomes.