What is it about?

In our opinion there are a lot of patients with pre-diabetes currently under-evaluated and under-treated. these patients also in condition of stable coronary disease could experience a worse prognosis. Therefore, the use of hypoglycemic drug could ameliorate clinical outcomes.

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Why is it important?

The treatment with metformin could ameliorate clinical outcomes in patients with prediabetes.

Perspectives

For the future new trials will investigate this worse clinical condition.

Celestino Sardu
University of Campania “Luigi Vanvitelli”

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This page is a summary of: Effects of Metformin Therapy on Coronary Endothelial Dysfunction in Patients With Prediabetes With Stable Angina and Nonobstructive Coronary Artery Stenosis: The CODYCE Multicenter Prospective Study, Diabetes Care, February 2019, American Diabetes Association,
DOI: 10.2337/dc18-2356.
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