β-Cell Secretory Capacity Predicts Metabolic Outcomes over 6 Years following Human Islet Transplantation

What is it about?

We investigated how functional beta-cell mass relates to metabolic control long-term following human islet transplantation and found a functional β-cell mass of >40% provides sufficient islet reserve for sustained insulin-independence but that marked glycemic control benefits are already attained by >20% normal.

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