Dental pulp stem cells for in vivo bone tissue engineering

What is it about?

We reviewed the current literature about the potential use of mesenchymal stem cells, isolated from dental pulp of permanent and deciduous teeth, for in vivo bone regeneration. The overall evidences highlighted that mesenchymal stem cells from dental pulp, supported by a suitable scaffold, can be considered a valuable source for bone tissue regeneration procedures.

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Why is it important?

Adult mesenchymal stem cells are currently used to develop regenerative medicine procedures. Bone marrow and adipose tissue have up to now represented the most used stem cell source; however the procedures required to harvest the cells are invasive. Dental pulp represents a promising source of stem cells, requiring a much less invasive and expensive method of cell isolation.