What is it about?
The study involves the silencing of the MYC gene in the breast cancer cell line , MCF-7, using functionalised gold nanoparticles. This study further shows the important role of polyethyleneglycol (PEG) stabilisation in achieving high gene silencing. The study with some optimisation, has potential for clinical application.
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This page is a summary of: Sterically stabilized siRNA:gold nanocomplexes enhance c-MYC silencing in a breast cancer cell model, Nanomedicine, June 2019, Future Medicine,
DOI: 10.2217/nnm-2018-0462.
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