What is it about?

The promises for NGS in breast cancer are tremendous for increasing our understanding of the disease, to identify new treatment targets and to move towards genome-informed personalized medicine

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Why is it important?

Progress is required in understanding physical and functional networks of interacting DNA, noncoding RNAs including miRNAs, proteins and other molecules. As we are moving from a single key factor and reductionist methods to ‘cloud networks and motifs’ for understanding complex multifactorial diseases, similarly, the drug discovery pipeline is shifting into global inhibition of perturbed signaling transduction pathway networks.

Perspectives

Advances in genome science and dynamic network biology guide the future.

Dr Demosthenes E. Ziogas
Peripheral General Hospital of Ioannina - Xatzikosta

Read the Original

This page is a summary of: Genome-based approaches for the diagnosis of breast cancer: a review with perspective, Breast Cancer Management, March 2014, Future Medicine,
DOI: 10.2217/bmt.13.81.
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