What is it about?
Probiotics are those microbes which reside in out gut as normal flora and help maintain a healthy body. There is growing interest these days to find out probiotics' potential as therapeutic agent. The major probiotics are gram positive bacteria like Lactobacillus, Bifidobacterium and Streptococcus. These isolates have been studied for treatment of metabolic syndromes like diabetes, obesity,; GIT infections like acute gastroenteritis, antibiotic associated diarrhea; hepatic encephalopathy; vaginal dysbiosis; even in some respiratory infections. Probiotics are also being explored as vaccine adjuvant and in fecal microbial transplant. The review article gives an update on all these aspects with future potential of probiotic therapy.
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Why is it important?
There is lot of potential therapeutic role of probiotics in ameliorating multiple infections, such as upper respiratory tract infections and viral respiratory infections, including COVID-19; liver diseases and hepatic encephalopathy; neurological and psychiatric disorders; autoimmune diseases, particularly rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis. Number of upcoming and new thrust areas have come up where probiotics are showing promising results, like fecal microbial transplant and vaginal microbial transplant
Perspectives
The objective of bringing out this review article was to update our understanding on probiotic potential in therapy. They can prove to be a very promising alternative to many chemical based drugs and reduce toxicity related with chemotherapeutic agents.
Aditi Singh
Amity University
Read the Original
This page is a summary of: Can the Therapeutic Spectrum of Probiotics be Extended: Exploring
Potential of Gut Microbiome, Recent Advances in Anti-Infective Drug Discovery, August 2023, Bentham Science Publishers,
DOI: 10.2174/2772434418666221124124317.
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