What is it about?
The combination of TQ and MET is considered a promising anticancer therapy to treat breast cancer induced by diabetes and nondiabetes mice. This combination possesses antiproliferative activity, anti-hyperglycemic activity, inhibits angiogenesis, and induces apoptosis. Furthermore, this combination demonstrated low toxicity.
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Why is it important?
A limited number of natural products have been tested for their antiproliferative effects against different cancers in diabetic mice. However, no studies have been conducted to assess the antitumor effect of thymoquinone and metformin combination in diabetic tumor-bearing mice.
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This page is a summary of: Targeting Breast Cancer in Diabetic Mice Using a Combination of Thymoquinone and Metformin, The Natural Products Journal, June 2022, Bentham Science Publishers,
DOI: 10.2174/2210315512666220615114025.
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