What is it about?
Soyasapogenol B (SB), aglycone of soybean saponin, is known to have hepatoprotective, antimutagenic, antivirus, and anti-inflammatory activities. This study is investigating SB production using whole cells producing saponin hydrolase in the enzyme reaction mixture.
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Why is it important?
Merits of the suggested method include; simplicity, relatively high SB yield, cost effective and easy downstream processing of products. The current results could be the groundwork for production of SB, such an important drug candidate, from soybean saponin on an industrial scale.
Perspectives
Microbial biotransformation by the whole cell microorganisms is often advantageous as compared to isolated enzymes; it is respected economically and ecologically a competitive tool for manufacturing clean valuable pharmaceutical compounds such as soyasapogenol B (SB). In this study, SB was produced by an enzyme reaction using Aspergillus flavus whole-cells producing saponin hydrolase enzyme.
Dr Hala A Amin
NRC Egypt
Read the Original
This page is a summary of: Whole Cell Biocatalyst for Soyasapogenol B Production from Soybean Saponin, The Open Conference Proceedings Journal, September 2016, Bentham Science Publishers,
DOI: 10.2174/2210289201607010134.
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