What is it about?
Periodontitis, a leading cause of tooth loss in adults, is a complex, multifactorial and inflammatory disease of the supporting structures of the teeth, characterized by an exaggerated gingival inflammatory response, causing alveolar bone loss and tooth loss if left untreated.
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Why is it important?
Periodontal disease is associated with systemic inflammation. In this context, there may be a bi-directional relationship between periodontal disease and Polycystic Ovarian Syndrome (PCOS) which is associated with low-grade systemic inflammation. PCOS is characterized by menstrual irregularities, chronic anovulation and hyperandrogenism. It is the most prevalent endocrinopathy in women of reproductive age, with a global prevalence ranging from 6% to 15%.
Perspectives
Our meta-analysis demonstrated that women diagnosed with PCOS showed a significantly higher association with periodontal disease than the healthy cohort within the limits of the available evidence. The significance of this association should be emphasized during the management of PCOS patients, by referring the patients to dentists or periodontists for regular mechanical debridement of plaque and periodontal maintenance. Such dental treatment will prevent the risk of developing periodontal disease and subsequent dentition loss in patients with PCOS.
Dr Ka Ting Ng
University of Malaya
Read the Original
This page is a summary of: Association of Periodontal Disease and Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis with Trial Sequential Analysis, The Open Dentistry Journal, December 2019, Bentham Science Publishers,
DOI: 10.2174/1874210601913010478.
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