What is it about?
This form of fibrous dysplasia, generally localized to pelvis and femur, results in a fragile bone with deformities, pain, pathological fractures and functional impairment. Intramuscular myxomas, generally rare benign mesenchymal neoplasms, exceptionally may evolve to malignant forms.
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Why is it important?
Zoledronic acid therapy rapidly lowered bone pain together with a reduction of intramuscular myxoma volume.
Perspectives
Zoledronic acid may represent a promising alternative to surgical intervention in this syndrome, although it has to be further confirmed.
Dr. ALBERTO FALCHETTI
Endosmet, Villa Donatello, Private Hospital, FLorence, Italy
Read the Original
This page is a summary of: Mazabraud's Syndrome: A Case Report And Up-To-Date Literature Review., Endocrine Metabolic & Immune Disorders - Drug Targets, December 2018, Bentham Science Publishers,
DOI: 10.2174/1871530319666181226103700.
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