What is it about?

Bee venom has been used, for quite a long time, to treat many inflammatory disorders. However, the exact mechanism of action is still to be unraveled regarding especially the venom of the Mediterranean bee species. Our research team is investigating the immunomodulatory effect of this venom in a mice model.

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Why is it important?

The importance of this study lies in determining the major effects of bee venom on the levels of several key cytokines that can shape the course and outcome of immune responses.

Perspectives

Bee (and other insects) venom, as crude or via its different fractions, can have deep impact on the immune system polarization. Therefore, targeting one or more steps of the immune response via a venom might modulate the outcome of such response toward therapeutic strategies related to several disorders such as inflammatory conditions, autoimmune diseases, pain/hyperalgesia and cancer among others.

Marc Karam
University of Balamand

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This page is a summary of: Apis mellifera syriaca Venom Modulates Splenic Cytokines Levels in BALB/c Mice, Infectious Disorders - Drug Targets, February 2024, Bentham Science Publishers,
DOI: 10.2174/1871526523666230623152045.
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