What is it about?
The article talks about the therapeutic potential and application of honokiol compound to target one of the mutations causing breast cancer.
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Why is it important?
A very few research papers have discussed this specific mutation and this is one of the rising mutations leading to deadly breast cancer. Targeting this mutation through honokiol can lead to the development of a non-cytotoxic and specific drug saving lives.
Perspectives
Breast cancer is the deadliest cancers among women and one of the leading causes of mortality. The ratio of this cancer is increasing globally and several new mutations are being discovered which limit the use of existing therapeutics. This manuscript is an attempt to target a rare mutation in breast cancer and to check the effectiveness of a plant-based compound for the development of non-cytotoxic drug.
Izzah Shahid
University of Central Punjab
Read the Original
This page is a summary of: In-silico Evaluation of Novel Honokiol Derivatives against Breast Cancer Target
Protein LKB1, Anti-Cancer Agents in Medicinal Chemistry, July 2023, Bentham Science Publishers,
DOI: 10.2174/1871520623666230330083630.
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