What is it about?

Meniscal injuries are one of the common sports injuries and their natural healing is limited. Removal of injured meniscus alters knee biomechanics and predisposes patients to osteoarthritis. Tissue engineered meniscus provides a novel approach for the treatment of severe meniscus injury. The aim of this review is to review preclinical studies that used cell based approaches for tissue engineered meniscus.

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Why is it important?

All preclinical studies that used cell based approaches for meniscus regeneration were included in the study.

Perspectives

Overall,experiments have demonstrated superior tissue integration and favourable biochemical properties of the regenerated tissues compared to acellular techniques.

Dr Amir Pakravan
University of Suffolk

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This page is a summary of: A Systematic Review of Tissue Engineered Meniscus Strategies: Experimental Preclinical Studies, Current Stem Cell Research & Therapy, February 2013, Bentham Science Publishers,
DOI: 10.2174/1574888x112079990046.
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