What is it about?
Ibopamine eye drops are used in Ophthalmology. This molecule is characterized by a dual mechanism of action, since it acts on both adrenergic and dopaminergic receptors. The adrenergic action is responsible for a marked mydriasis without accomodative paralysis, while the dopaminergic action increases the production of aqueous humor. Given this dual action, ibopamine may be useful for diagnostic purposes in Ophthalmology. This paper aims at presenting the most intriguing evidence on ibopamine and discusses the profile of patients who may be best suitable to this molecule.
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Why is it important?
It is an important drug due to its dual mechanism of action. It is useful from the diagnostic point of view in glaucoma and suspected glaucoma patients because it is a provocative test. It is useful to examine fundus oculi because it is a mydriatic drug. It is useful together with corticosteroids to increase intraocular pressure in hypotonic eyeballs.
Perspectives
There are a lot of papers on this topic. Mostly it can be useful in relatives of glaucomatous patients for an early diagnosis.
Dr Italo Giuffre'
Catholic University of Rome
Read the Original
This page is a summary of: Ibopamine Stimulates α-Adrenergic Receptors and D1 Dopaminergic Receptors in the Eye, Current Drug Therapy, May 2007, Bentham Science Publishers,
DOI: 10.2174/157488507780619112.
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