What is it about?
Stilbene is a class of plant-derived phenolic compounds with a variety of biological activities, including anticancer and antitumor. We explore its interaction with Bcl-2 proteins, a group of proteins which prevent cell death in cancers. We applied in silico molecular docking to determine how well these compounds fit with the Bcl-2 proteins to block its function.
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Why is it important?
Our findings contribute to the endeavor to identify potential treatments for cancer cell death, offering a promising approach for therapies by selecting lead compounds for cancer drug discovery.
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This page is a summary of: Stilbene-based Derivatives as Potential Inhibitors of Bcl-2 Antiapoptotic Proteins: A Molecular Docking Study and ADMET Prediction, Letters in Drug Design & Discovery, September 2024, Bentham Science Publishers,
DOI: 10.2174/1570180820666230911130135.
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