Osteoprotegerin and Diabetes-Associated Pathologies

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Why is it important?

It is a complete review of the literature, evidencing not only how increased levels of osteoprotegerin in plasma correlate to diabetes but also the possible effect of bad glycemic control and elevated blood pressure on osteoprotegerin levels in plasma. The review also includes several figures showing the mechanisms that link osteoprotegerin to endothelial dysfunction, diabetic nephropathy, atherosclerosis and fibrosis.