What is it about?
This paper deals with the role of a specific growth factor (Hepatocyte growth factor) in the pathogenesis of lymphomas. In particular the activity of HGF has been explored in more details in Chronic Lymphocytic Leukemia.
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Why is it important?
Up to now only a few papers have considered the activity of Hepatocyte growth factor in supporting the clonal expansion of leukemic cells. Moreover we interestingly highlighted a dual role of HGF: increased survival of leukemic cells and suppression of the control of the disease by immune cells
Perspectives
The role of Hepatocyte growth factor in lymphomas appears to be relevant but not too much explored. The study of this cytokine thus deserves additional attention from the scientific community and is still a relatively open field research.
Daniela de Totero
Read the Original
This page is a summary of: Survival and Immunosuppression Induced by Hepatocyte Growth Factor in Chronic Lymphocytic Leukemia, Current Molecular Medicine, April 2017, Bentham Science Publishers,
DOI: 10.2174/1566524017666170220095838.
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