Exploration and Scope of Aromatase Inhibitors in Breast Cancer Therapy

What is it about?

This is a review on research path of aromatase inhibitors, their progress to the status of first line drugs in the breast cancer therapy, several new software technologies and innovative approaches in the aromatase inhibitors research, the unexplored facets and rational approaches to keep the aromatase inhibitors research at the forefront in the fight of complete cure for Breast cancer.

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Why is it important?

The aromatase in-silico simulation studies, resistance pathways in the breast cancer helps to design new class of drugs that target multiple enzyme receptors along with aromatase which affect the estrogen synthesis, other resistance pathways and control other side effects in the treatment of breast cancer. The design of radiolabeled aromatase inhibitors is one key area which helps to trace distribution of drug, diagnoses and the treatment progress of the disease using PET or SPECT. The way forward in the treatment of breast cancer should be a multidisciplinary holistic approach.