What is it about?
This work is concerned with the evaluation of anti-stress bioactive compounds from the ethanolic root extract of Hemidesmus indicus.
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Why is it important?
The identified compounds were used for anti-stress activity by insilico method with Vasopressin which plays an important role in causing stress and hence selected for inhibitory studies with phytocompounds. The phytocompounds are inhibiting Vasopressin through hydrogen bodings and are important in protein-ligand interactions. Docking results showed that out of twenty one compounds, Deoxiinositol, pentakis-O-(trimethylsilyl) showed best docking energy to the Vasopressin.
Perspectives
the activity of phytocompounds and the development of phytocompounds as drugs can be improved by docking studies, which is the main aspect of this work.
jayasimharayalu daddam
Read the Original
This page is a summary of: In Silico Studies on Anti-Stress Compounds of Ethanolic Root Extract of Hemidesmus indicus L., Current Pharmaceutical Biotechnology, May 2020, Bentham Science Publishers,
DOI: 10.2174/1389201021666191211152754.
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