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At sites of local inflammation and tissue injury it may bind to phosphocholine-rich membranes of activated and apoptotic cells and their microparticles, undergoing irreversible dissociation to five monomeric subunits, termed monomeric CRP (mCRP). In this mini-review, we will provide an insight into the process of conformational rearrangement of native pentameric form of CRP, leading to dissociation, and describe known effects of mCRP.
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This page is a summary of: Current position on the role of monomeric C-reactive protein in vascular pathology and atherothrombosis., Current Pharmaceutical Design, December 2019, Bentham Science Publishers,
DOI: 10.2174/1381612825666191216144055.
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