What is it about?
Stilbene is a class of plant-derived phenolic compounds with a variety of biological activities, including anticancer and antitumor. We explore its interaction with Bcl-2 proteins, a group of proteins which prevent cell death in cancers. We applied in silico molecular docking to determine how well these compounds fit with the Bcl-2 proteins to block its function.
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Photo by National Cancer Institute on Unsplash
Why is it important?
Our findings contribute to the endeavor to identify potential treatments for cancer cell death, offering a promising approach for therapies by selecting lead compounds for cancer drug discovery.
Perspectives
Research and discovery have always been my interests. The opportunity to participate in this research and contribute to writing this paper has provided me with great satisfaction in my journey as a researcher. Together with my esteemed co-authors, we hope to make science more appealing to the masses.
Mohamad Norisham Mohamad Norisham
Universiti Malaysia Sabah
Read the Original
This page is a summary of: Stilbene-based Derivatives as Potential Inhibitors of Bcl-2 Antiapoptotic Proteins: A Molecular Docking Study and ADMET Prediction, Letters in Drug Design & Discovery, September 2024, Bentham Science Publishers,
DOI: 10.2174/1570180820666230911130135.
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