Strategies to improve the escape of gene delivery platforms from endosomes
What is it about?
Endosome entrapment is a key barrier to the success of non-viral gene delivery systems. This review details various methods that have been investigated to improve the escape of delivered genes/oligonucleotides from endosomes following their cellular uptake.
Why is it important?
Endosome escape is a very important barrier to the success of non-viral gene delivery systems. This review provides important examples of successful approaches to improve the endosome escape of genes. This information is essential for the successful development of non-viral gene delivery systems.
The following have contributed to this page: Dr Peter Michael Moyle