Development of antiseizure medications

What is it about?

Epilepsy is a brain condition that affects millions of people around the world. The main way doctors treat it is with special medicines that help prevent seizures, called anti-seizure medications (ASMs). This review focuses on how some new ASMs work and the major challenges in developing them, like when patients do not respond to them (called drug-resistant epilepsy), or when the medicines cause mood or behavior problems. Another topic we explore is what happens when doctors use more than one ASM at a time (called polytherapy), including the pros and cons of this approach. The review also talks about what an "ideal" seizure medication would look like—something effective, safe, and easy to take. Finally, we explain how certain brain signals might be key to controlling seizures.

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Photo by Pawel Czerwinski on Unsplash

Photo by Pawel Czerwinski on Unsplash