Anti – Gene IGF-I Vaccines in Cancer Gene Therapy: Case of Glioblastoma

“

Brain tumor - Glioblastoma is the most common malignant pathology of central nervous system, with median survival - less than a year in most cases. So, the search of treatment solution constitutes the permanent battle from at least the half of last century, including different technics such as radio and chemotherapy, growth factors inhibitors, immunotherapy and especially cancer gene therapy, the last demonstrating the clinical success. The history of this new way in oncology was described in a recently published book (J. Trojan. Establishment of cancer gene therapy. Cambridge Schol. Pub. 2023). To increase the efficiency of anti-tumor immune response, this strategy will be combined with use of phytochemicals and nanotechnology, constituting my research in progress.

”