What is it about?
The goal of the current investigation was to explore the nephrotoxicity of BPA using biochemical, genetical, and histopathological examinations of the kidneys of male mice. Besides, to investigate the role of pumpkin and linseed oils in alleviating the toxicity of BPA in mouse kidneys,.
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Why is it important?
Edible plant oils have been made known to be exciting sources of bioactive compounds, making them a suitable alternative in the management of some human diseases. Pumpkin and linseed oils are high in Omega-3 & Omega-6, which are considered the most vital essential fatty acids that the body cannot create and are considered crucial for health. Bisphenol-A (BPA) plays a role in the development of chronic kidney disease, particularly in developing countries with high levels of pollution.
Perspectives
Our results indicate that pumpkin and linseed oils can increase DNA integrity and ameliorate the histopathological defects in the kidney tissues of BPA-treated mice. The current study found that pumpkin and linseed oils have promising attenuating activity against the unwanted properties of BPA.
Professor Aida Ibrahim El makawy
Read the Original
This page is a summary of: Role of Pumpkin and Linseed Oils in Attenuating the Nephrotoxicity of Bisphenol-A in Mice: Biochemical, Genetic and Histopathological studies, Egyptian Journal of Chemistry, April 2022, Egypts Presidential Specialized Council for Education and Scientific Research,
DOI: 10.21608/ejchem.2022.122316.5475.
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