What is it about?
We aimed in this study to determine the association of I/D polymorphism of α2B-adrenergic receptor with hypertension with and without type 2 diabetes mellitus (T2DM) and to show role of type 2 diabetes mellitus in this association
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Why is it important?
In conclusion, our study showed stronger association of DD genotype and D allele with hypertension and this association is more evident in hypertension with diabetes that postulate that deletion allele is associated with diabetes so α2B-AR polymorphism is one of genes involved in prediction of hypertension and diabetesthe α-2 adrenergic receptor pathway should be considered as a potential drug target for prevention of type 2 diabetes.
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This page is a summary of: Association of deletion allele of insertion/deletion polymorphism in α2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus, The Application of Clinical Genetics, December 2012, Taylor & Francis,
DOI: 10.2147/tacg.s33814.
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